Special Section on BioMEMS, Theory and Practice of MEMS/NEMS, and Sensors

Trapping of hyaluronic acid molecule by metal-coated silicon nanotweezers

[+] Author Affiliations
Takashi Mineta, Hiroko Takeuchi, Eiji Makino

Hirosaki University, Graduate School of Science and Technology, Hirosaki, Japan

Gen Hashiguchi

Shizuoka University, Research Institute of Electronics, Shizuoka, Japan

J. Micro/Nanolith. MEMS MOEMS. 9(3), 031004 (July 06, 2010). doi:10.1117/1.3455369
History: Received September 25, 2009; Revised December 31, 2009; Accepted January 06, 2010; Published July 06, 2010; Online July 06, 2010
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We describe the trapping characteristic of hyaluronic acid (HA) molecules using silicon micromachined nanotweezers having two opposed needle tips (37μm gap) that were coated with Al, Au, and Pt thin films. In an aqueous HA solution, ac voltage (20Vpp, sine wave) was applied between the nanotweezer tips. In the experiments using the Al-coated nanotweezers, HA molecules were successfully trapped as a thin string bridged between the tips of the nanotweezers when the frequency of applied ac voltage was 500Hz or higher. The diameter of the trapped string tended to decrease when the frequency of the applied ac voltage was increased. A molecular string with a diameter of 30nm consisting of a bundle of multiple HA molecules was obtained when the frequency of the applied ac voltage was 3kHz. In addition to the Al-coated nanotweezers, HA molecules were also successfully trapped as a string using the nanotweezers with tips coated with Au and Pt thin films.

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© 2010 Society of Photo-Optical Instrumentation Engineers

Topics

Metals ; Molecules ; Silicon

Citation

Takashi Mineta ; Hiroko Takeuchi ; Eiji Makino and Gen Hashiguchi
"Trapping of hyaluronic acid molecule by metal-coated silicon nanotweezers", J. Micro/Nanolith. MEMS MOEMS. 9(3), 031004 (July 06, 2010). ; http://dx.doi.org/10.1117/1.3455369


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