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In vivo thermal evaluation of a subretinal prosthesis using an integrated resistance temperature detector

[+] Author Affiliations
Ching-Yu Liu

National Tsing Hua University, Institute of Nanoengineering & Microsystems, No. 101, Sec. 2, Kuang-Fu Road, Hsinchu, Taiwan 30013

Frank Yang, Chia-He Chung, Zung-Hua Yang

National Tsing Hua University, Institute of Nanoengineering & Microsystems, No. 101, Sec. 2, Kuang-Fu Road, Hsinchu, Taiwan 30013

Ta-Ching Chen, Chang-Hao Yang, Chung-May Yang

National Taiwan University Hospital, Department of Ophthalmology and National Taiwan University, College of Medicine, No. 1, Sec. 4, Roosevelt Road, Taipei, Taiwan 10051

Long-Sheng Fan

National Tsing Hua University, Institute of Nanoengineering & Microsystems, No. 101, Sec. 2, Kuang-Fu Road, Hsinchu, Taiwan 30013

J. Micro/Nanolith. MEMS MOEMS. 13(1), 013006 (Feb 05, 2014). doi:10.1117/1.JMM.13.1.013006
History: Received November 23, 2013; Revised December 14, 2013; Accepted December 27, 2013
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Abstract.  The temperature rise from the operation of implanted biomedical devices should be kept within a safe limit to prevent thermal damage or any undesirable thermal effects. To evaluate the temperature rise from the operation of an implanted high-density microelectrodes array (MEA) on a flex in the subretinal space, we directly integrated resistance temperature detectors into this retinal MEA device in the same micro fabrication. We surgically implanted this MEA device in the subretinal space of a rabbit model and measured the temperature rise in vivo. The measured temperature rise is consistent with the calculated values from the finite element method. Experiment showed the temperature versus power dissipation of the MEA device had a slope of 0.84°C/(mW·mm2). To ensure the temperature rise is within 1.0°C, the maximum power dissipation on the retinal implant should be kept within 1.2mW·mm2.

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© 2014 Society of Photo-Optical Instrumentation Engineers

Topics

Resistance ; Sensors ; Eye

Citation

Ching-Yu Liu ; Frank Yang ; Chia-He Chung ; Zung-Hua Yang ; Ta-Ching Chen, et al.
"In vivo thermal evaluation of a subretinal prosthesis using an integrated resistance temperature detector", J. Micro/Nanolith. MEMS MOEMS. 13(1), 013006 (Feb 05, 2014). ; http://dx.doi.org/10.1117/1.JMM.13.1.013006


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