Sensitivity enhancement of nickel nanowire-gated FET glucose sensor using graphene film as intermediate layer

Sheng-Chun Hung; Chia-Chi Chen; Yu-Cheng Lin; Chung-Wei Lin; Wei-Lun Chen; Wen-Hung Chien; Jhih-Syuan Huang

doi:10.1117/12.3005584

20 September 2023 Sensitivity enhancement of nickel nanowire-gated FET glucose sensor using graphene film as intermediate layer

Sheng-Chun Hung, Chia-Chi Chen, Yu-Cheng Lin, Chung-Wei Lin, Wei-Lun Chen, Wen-Hung Chien, Jhih-Syuan Huang

Author Affiliations +

Proceedings Volume 12608, Biomedical Imaging and Sensing Conference; 1260803 (2023) https://doi.org/10.1117/12.3005584
Event: Optics and Photonics International Congress, 2023, Yokohama, Japan

Abstract

In this work, an innovative noninvasive nickel wire-gated FET glucose sensor with and without graphene film as an intermediate layer was investigated. According to the redox reactions between nickel nanowires and glucose molecules in weak alkaline solutions, electron exchange occurs when Ni (III) reacts with glucose to form Ni (II) and glucolactone. However, the generated electrons are usually neutralized prematurely due to material defects. This study investigates the electrical effects of using graphene as an intermediate layer between Ni nanowires and gate metal. Compared with the glucose FET sensor using nickel nanowires alone as the gate metal, due to the good electrical conductivity of the graphene film under the nickel nanowires in the gate area, the electrons generated by the nickel nanowires catalyzing glucose molecules can quickly dispersed on the metal surface via the graphene film, which will enhance the change of the gate potential, and the sensitivity of the FET glucose detector is further improved. This experiment shows that the detection limit of a transistor-based glucose detector with a nickel nanowire gate is 551.2 μM and 51 nM, respectively, without and with graphene as an intermediate layer.

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Sheng-Chun Hung, Chia-Chi Chen, Yu-Cheng Lin, Chung-Wei Lin, Wei-Lun Chen, Wen-Hung Chien, and Jhih-Syuan Huang "Sensitivity enhancement of nickel nanowire-gated FET glucose sensor using graphene film as intermediate layer", Proc. SPIE 12608, Biomedical Imaging and Sensing Conference, 1260803 (20 September 2023); https://doi.org/10.1117/12.3005584

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KEYWORDS

Glucose

Sensors

Nickel

Graphene

Nanowires

Field effect transistors

Blood

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