A model for simulation of electrically evoked auditory brainstem responses

Douglas A. Miller; Mohammed A. Matin

doi:10.1117/12.829349

1 September 2009 A model for simulation of electrically evoked auditory brainstem responses

Proceedings Volume 7442, Optics and Photonics for Information Processing III; 74421E (2009) https://doi.org/10.1117/12.829349
Event: SPIE Optical Engineering + Applications, 2009, San Diego, California, United States

Abstract

An important aspect of research in the continued development of cochlear implants is the in vivo assessment of signal processing algorithms. One technique that has been used is evoked potentials, the recording of neural responses to auditory stimulation. Depending on the latency of the observed response, the evoked potential indicates neural activity at the various neurological structures of the auditory system. Electrically evoked ABRs are commonly measured in hearing-impaired patients who have cochlear implants, via electrical stimulation delivered by electrodes in the implanted array. This research explores the use of MATLAB for the purpose of developing a model for electrically evoked auditory brainstem responses (ABRs). The simulation model developed in this study takes as its input the stimulus current intensity level, and uses function vectors and equations derived from measured ABRs, to generate an approximation of the evoked surface potentials. A function vector is used to represent the combined firing of the neurons of the auditory nervous system that are needed to elicit a measurable response. Equations have been derived to represent the latency and stimulus amplitude scaling functions. The simulation also accounts for other neural activity that can be present in and contaminate an ABR recording, and reduces it through time-locked averaging of the simulated response. In the MATLAB simulation, the model performs well and delivers results that compare favorably with the results measured from the research subjects.

Citation Download Citation

Douglas A. Miller and Mohammed A. Matin "A model for simulation of electrically evoked auditory brainstem responses", Proc. SPIE 7442, Optics and Photonics for Information Processing III, 74421E (1 September 2009); https://doi.org/10.1117/12.829349

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available