Evaluation of an affinity-amplified immunoassay of graphene oxide using surface plasmon resonance biosensors

Nan-Fu Chiu; Teng-Yi Huang; Chun-Chuan Kuo

doi:10.1117/12.2182134

5 May 2015 Evaluation of an affinity-amplified immunoassay of graphene oxide using surface plasmon resonance biosensors

Nan-Fu Chiu, Teng-Yi Huang, Chun-Chuan Kuo

Proceedings Volume 9506, Optical Sensors 2015; 95061H (2015) https://doi.org/10.1117/12.2182134
Event: SPIE Optics + Optoelectronics, 2015, Prague, Czech Republic

Abstract

We describe a fundamental study on the plasmonic properties and advanced biosensing mechanisms of functionalized graphene. We discuss a specific design using modified carboxyl groups, which can modulate surface plasmon (SP) coupling and provide an advantage for their binding to the sensing layer with high-performance affinity in an immunological reaction. The functionalized graphene-based surface plasmon resonance (SPR) biosensors have three advantages: high performance, high sensitivity, and excellent molecular kinetic response. In the future, functionalized graphene sheets will make a unique contribution to photonic and SPR diagnosis devices. We wish to highlight the essential characteristics of functionalized graphene-based SPR biosensors to assist researchers in developing and advancing suitable biosensors for unique applications.

Citation Download Citation

Nan-Fu Chiu, Teng-Yi Huang, and Chun-Chuan Kuo "Evaluation of an affinity-amplified immunoassay of graphene oxide using surface plasmon resonance biosensors", Proc. SPIE 9506, Optical Sensors 2015, 95061H (5 May 2015); https://doi.org/10.1117/12.2182134

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