Prof. Radim Chmelík
Professor at Brno University of Technology
SPIE Involvement:
Author
Area of Expertise:
quantitative phase imaging , wave optics , visual optics , holographic microscopy , imaging through turbid media
Websites:
Profile Summary

Professor Radim Chmelik studied physics at Masaryk University Brno and in 1997 received his PhD in Physical and Materials Engineering from Brno University of Technology (Czech Republic) under Professor Jiri Komrska for the theoretical description of focusing by diffractive lenses. As a postdoc, he studied methods of 3D imaging in light microscopy. This led him to incoherent holography approaches. In the late ninetieth, he and Professor Zdenek Harna built the first holographic microscope capable of working with completely incoherent illumination. He then continued to investigate these techniques as modalities of quantitative phase imaging (QPI) and (since 2007) their applications in cell biology with Dr. Pavel Vesely. In 2012, Radim Chmelik became the head of the Experimental Biophotonics research group at CEITEC, Brno. Within the field of advanced light microscopy, his group focuses on the progress of Holographic Incoherent QPI (hiQPI) both in the development and applications. Coherence effects are studied to develop hiQPI of 3D specimens and improve imaging in turbid media. Novel techniques and image processing methods are applied to non-invasive live cell behavior analysis. Based on live-cell dry-mass profiling, the responses to therapeutic challenges constitute the strategy for developing personalized cancer treatment. Radim Chmelik recently received the Czech Brains award in the invention prize category.
Publications (31)

Proceedings Article | 3 December 2021 Paper
Markéta Šuráňová, Daniel Zicha, Pavel Veselý, Jan Brábek, Veronika Jůzová, Radim Chmelík
Proceedings Volume 11921, 119210K (2021) https://doi.org/10.1117/12.2615638
KEYWORDS: Cancer, Tumors, Holography, Phase imaging, In vitro testing, Optical design, Image segmentation, Image processing, Therapeutics, Resistance

SPIE Journal Paper | 18 August 2020 Open Access
Lenka Strbkova, Brittany B. Carson, Theresa Vincent, Pavel Vesely, Radim Chmelik
JBO, Vol. 25, Issue 08, 086502, (August 2020) https://doi.org/10.1117/12.10.1117/1.JBO.25.8.086502
KEYWORDS: Machine learning, Feature extraction, Image classification, Image segmentation, Digital holography, Microscopy, Holography, Principal component analysis, Cell mechanics

Proceedings Article | 24 May 2018 Presentation + Paper
Radim Chmelik, Miroslav Duris, Lenka Strbkova
Proceedings Volume 10677, 106771C (2018) https://doi.org/10.1117/12.2309907
KEYWORDS: Scattering, Photons, Light scattering, Image quality, Holography, Phase imaging, Coherence (optics), Optical microscopy, Microscopy, Diffuse optical imaging, Quantitative analysis, Phase contrast

SPIE Journal Paper | 23 August 2017 Open Access
Lenka Strbkova, Daniel Zicha, Pavel Vesely, Radim Chmelik
JBO, Vol. 22, Issue 08, 086008, (August 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.8.086008
KEYWORDS: Microscopy, Molybdenum, Image segmentation, Machine learning, Image classification, Holography, Feature extraction, Phase imaging, Databases, Cancer

Proceedings Article | 24 April 2017 Presentation
Martin Plöschner, Véra Kollárová, Zbyněk Dostál, Jonathan Nylk, Thomas Barton-Owen, David E. Ferrier, Radim Chmelik, Kishan Dholakia, Tomáš Cizmár
Proceedings Volume 10073, 1007305 (2017) https://doi.org/10.1117/12.2250694
KEYWORDS: Tissue optics, Tissues, Microscopy, Multimode fibers, Endoscopy, Holography, Imaging systems, Luminescence, Biology, 3D image processing

Showing 5 of 31 publications
Conference Committee Involvement (9)
Holography: Advances and Modern Trends IX
7 April 2025 | Prague, Czech Republic
Holography: Advances and Modern Trends VIII
24 April 2023 | Prague, Czech Republic
Holography: Advances and Modern Trends VII
19 April 2021 | Online Only, Czech Republic
Holography: Advances and Modern Trends
1 April 2019 | Prague, Czech Republic
Holography: Advances and Modern Trends
24 April 2017 | Prague, Czech Republic
Showing 5 of 9 Conference Committees
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