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Last year we introduced a new Full Field Optical Transmission Tomography (FFOTT) technique that we applied to CELL studies. This interferometric technique is based on the use of the Gouy phase shift that takes place close to a microscope objective focus. We will now show results obtained in biological tissues using both a static mode (morphology) and dynamic one (metabolic contrast). In particular we have been able with our 400 $ microscope to section in tissues. We will discuss the importance of the spatial coherence of the illumination and compare the results with those obtained with Full Field OCT.
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Claude Boccara, Samer Alhaddad, Olivier Thouvenin, Martine Boccara, Viacheslav Mazlin, "Towards optical tomography of tissues up to 100 times cheaper," Proc. SPIE PC12832, Optics and Biophotonics in Low-Resource Settings X, PC1283209 (13 March 2024); https://doi.org/10.1117/12.3001159