Preclinical x-ray dark-field imaging: foreign body detection

Eva-Maria Braig; Daniela Muenzel; Alexander Fingerle; Julia Herzen; Ernst Rummeny; Franz Pfeiffer; Peter Noel

doi:10.1117/12.2254261

9 March 2017 Preclinical x-ray dark-field imaging: foreign body detection

Eva-Maria Braig, Daniela Muenzel, Alexander Fingerle, Julia Herzen, Ernst Rummeny, Franz Pfeiffer, Peter Noel

Proceedings Volume 10132, Medical Imaging 2017: Physics of Medical Imaging; 101325G (2017) https://doi.org/10.1117/12.2254261
Event: SPIE Medical Imaging, 2017, Orlando, Florida, United States

Abstract

The purpose of this study was to evaluate the performance of X-ray dark-field imaging for detection of retained foreign bodies in ex-vivo hands and feet. X-ray dark-field imaging, acquired with a three-grating Talbot-Lau interferometer, has proven to provide access to sub-resolution structures due to small-angle scattering. The study was institutional review board (IRB) approved. Foreign body parts included pieces of wood and metal which were placed in a formalin fixated human ex-vivo hand. The samples were imaged with a grating-based interferometer consisting of a standard microfocus X-ray tube (60 kVp, 100 W) and a Varian 2520-DX detector (pixel size: 127 μm). The attenuation and the dark-field signals provide complementary diagnostic information for this clinical task. With regard to detecting of wooden objects, which are clinically the most relevant, only the dark-field image revealed the locations. The signal is especially strong for dry wood which in comparison is poorly to non-visible in computed tomography. The detection of high atomic-number or dense material and wood-like or porous materials in a single X-ray scan is enabled by the simultaneous acquisition of the conventional attenuation and dark-field signal. Our results reveal that with this approach one can reach a significantly improved sensitivity for detection of foreign bodies, while an easy implementation into the clinical arena is becoming feasible.

Citation Download Citation

Eva-Maria Braig, Daniela Muenzel, Alexander Fingerle, Julia Herzen, Ernst Rummeny, Franz Pfeiffer, and Peter Noel "Preclinical x-ray dark-field imaging: foreign body detection", Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101325G (9 March 2017); https://doi.org/10.1117/12.2254261

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