Dynamics of controllably induced bruises assessed by diffuse reflectance spectroscopy and pulsed photothermal radiometry

Ana Marin; Matija Milanič; Nina Verdel; Luka Vidovič; Boris Majaron

doi:10.1117/12.2289982

14 February 2018 Dynamics of controllably induced bruises assessed by diffuse reflectance spectroscopy and pulsed photothermal radiometry

Ana Marin, Matija Milanič, Nina Verdel, Luka Vidovič, Boris Majaron

Author Affiliations +

Proceedings Volume 10467, Photonics in Dermatology and Plastic Surgery 2018; 104670N (2018) https://doi.org/10.1117/12.2289982
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Combination of diffuse reflectance spectroscopy (DRS) and pulsed photothermal radiometry (PPTR) was recently successfully used to study evolution of accidental traumatic bruises. Yet, accidental bruises introduce many unknowns into the evolution analysis and thus a more controllable and repeatable approach for bruising is desired. In this study, evolution of bruises induced by aluminum projectiles of known mass and velocity were studied by DRS and PPTR. Bruises were induced on volar forearm skin of two healthy volunteers. Inverse Monte Carlo including four-layer skin model, was used to analyze the DRS and PPTR data to determine skin chromophores, their concentrations and depths. For bruise analysis, a bruise model was constructed and evolved according to hemoglobin diffusion kinetics. Bruise analysis of PPTR signals yielded bruise evolution parameters, most importantly hemoglobin diffusion constant, hemoglobin decomposition time and blood pool depth. The study results show that chronological tracking of hemoglobin decomposition can be assessed by the combined DRS and PPTR technique on induced bruise. Parameters of individual bruises were compared and two trends in chronological behavior of hemoglobin decomposition time discerned. Changes in bruise diffuse reflectance spectra were noted. Induced bruise parameters, however, still showed some scatter and thus further research is needed to reduce bruise variability.

Conference Presentation

Citation Download Citation

Ana Marin, Matija Milanič, Nina Verdel, Luka Vidovič, and Boris Majaron "Dynamics of controllably induced bruises assessed by diffuse reflectance spectroscopy and pulsed photothermal radiometry", Proc. SPIE 10467, Photonics in Dermatology and Plastic Surgery 2018, 104670N (14 February 2018); https://doi.org/10.1117/12.2289982

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