Towards bimodal intravascular OCT MPI volumetric imaging

Sarah Latus; Florian Griese; Matthias Gräser; Martin Möddel; Matthias Schlüter; Christoph Otte; Nils Gessert; Thore Saathoff; Tobias Knopp; Alexander Schlaefer

doi:10.1117/12.2293497

9 March 2018 Towards bimodal intravascular OCT MPI volumetric imaging

Sarah Latus, Florian Griese, Matthias Gräser, Martin Möddel, Matthias Schlüter, Christoph Otte, Nils Gessert, Thore Saathoff, Tobias Knopp, Alexander Schlaefer

Author Affiliations +

Proceedings Volume 10573, Medical Imaging 2018: Physics of Medical Imaging; 105732E (2018) https://doi.org/10.1117/12.2293497
Event: SPIE Medical Imaging, 2018, Houston, Texas, United States

Abstract

Magnetic Particle Imaging (MPI) is a tracer-based tomographic non-ionizing imaging method providing fully three-dimensional spatial information at a high temporal resolution without any limitation in penetration depth. One challenge for current preclinical MPI systems is its modest spatial resolution in the range of 1 mm - 5 mm. Intravascular Optical Coherence Tomography (IVOCT) on the other hand, has a very high spatial and temporal resolution, but it does not provide an accurate 3D positioning of the IVOCT images. In this work, we will show that MPI and OCT can be combined to reconstruct an accurate IVOCT volume. A center of mass trajectory is estimated from the MPI data as a basis to reconstruct the poses of the IVOCT images. The feasibility of bimodal IVOCT and MPI imaging is demonstrated with a series of 3D printed vessel phantoms.

Citation Download Citation

Sarah Latus, Florian Griese, Matthias Gräser, Martin Möddel, Matthias Schlüter, Christoph Otte, Nils Gessert, Thore Saathoff, Tobias Knopp, and Alexander Schlaefer "Towards bimodal intravascular OCT MPI volumetric imaging", Proc. SPIE 10573, Medical Imaging 2018: Physics of Medical Imaging, 105732E (9 March 2018); https://doi.org/10.1117/12.2293497

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