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Spatial Frequency Domain Imaging (SFDI) is a quantitative imaging method that measures optical properties of tissue. We present the design of a compact spectral imager to perform SFDI in low resource settings, which exploits a low-cost color CMOS camera and mini-projector. These devices are usually limited to three broad spectral bands (RGB). We have developed a novel method to extrapolate two additional wavelengths without hardware modifications, improving the spectral resolution of the device, allowing to account for additional sources of skin pigmentation. Our device performance was evaluated on tissue-simulating phantoms. In-vivo measurements were compared to a commercial probe-based system (EPOS).
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Luigi Belcastro, Hanna Jonasson, Tomas Strömberg, Rolf B. Saager, "Low cost handheld spectral imager for rapid skin assessment in low resource settings (Conference Presentation)," Proc. SPIE 11230, Optics and Biophotonics in Low-Resource Settings VI, 1123002 (9 March 2020); https://doi.org/10.1117/12.2543701