Optimization of SNR, sensitivity values by evaluating the relative spacing between the partial mirror and scanning reference mirror for multiple reference optical coherence tomography

Anand Arangath; Kai Neuhaus; Yi Zhou; Sergey Alexandrov; Josh Hogan; Carol Wilson; Martin Leahy

doi:10.1117/12.2550331

14 May 2020 Optimization of SNR, sensitivity values by evaluating the relative spacing between the partial mirror and scanning reference mirror for multiple reference optical coherence tomography

Anand Arangath, Kai Neuhaus, Yi Zhou, Sergey Alexandrov, Josh Hogan, Carol Wilson, Martin Leahy

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Proceedings Volume 11230, Optics and Biophotonics in Low-Resource Settings VI; 112300X (2020) https://doi.org/10.1117/12.2550331
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Multiple reference optical coherence tomography (MR-OCT) is a time-domain interferometric imaging platform which promises to be realized as a low cost, compact imaging technology. The optical configuration of MR-OCT makes use of multiple reflections between a partial mirror and the axially scanning reference mirror to enhance the axial imaging depth compared to the otherwise shallow scanning range of the voice coil or piezo actuator. Since each reflection on the partial mirror causes an optical path delay, the focusing of each higher order of reflection is changing. That means the beam diameter, beam collimation and therefore the interference visibility are changing as well. This investigation focuses on how the spacing between the partial mirror and the scanning mirror affects the system’s sensitivity and SNR values. The potential to improve the sensitivity of higher orders of reflections related to deeper regions in a sample will be studied.

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Anand Arangath, Kai Neuhaus, Yi Zhou, Sergey Alexandrov, Josh Hogan, Carol Wilson, and Martin Leahy "Optimization of SNR, sensitivity values by evaluating the relative spacing between the partial mirror and scanning reference mirror for multiple reference optical coherence tomography", Proc. SPIE 11230, Optics and Biophotonics in Low-Resource Settings VI, 112300X (14 May 2020); https://doi.org/10.1117/12.2550331

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KEYWORDS

Mirrors

Gaussian beams

Optical coherence tomography

Signal to noise ratio

Sensors

Actuators

Computing systems

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