Paper
21 February 2020 Multi-spectral vascular oximetry of rat dorsal spinal cord
Author Affiliations +
Abstract
We describe a visible-light multi-spectral system for vascular oximetry studies that can be implemented in lowand middle-income countries, using a low-cost electronics and optical elements, for instance a Raspberry Pi, a Pi camera under a resolution of 5-megapixel, 2592x1944-pixel resolution, and four different light sources at 480nm, 532nm, 593nm and 610nm on a singular structured illumination area. It is designed to quantify the vascular oxygen saturation change of the rat dorsal spinal cord, which uses a Phyton custom application that synchronize all elements to execute the imaging process in one system, powered by a portable rechargeable 5V battery pack. Aimed for drug discovery, tracking disease progression and understanding of progressive and degenerative diseases. By replacing expensive and bulky imaging systems.
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Victor Ochoa-Gutierrez, Pavan C. Konda, Sara Motaghian, Julien Reboud, Jonathan M. Cooper, and Andrew R. Harvey "Multi-spectral vascular oximetry of rat dorsal spinal cord", Proc. SPIE 11230, Optics and Biophotonics in Low-Resource Settings VI, 1123012 (21 February 2020); https://doi.org/10.1117/12.2558281
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KEYWORDS
Imaging systems

Oximetry

Spinal cord

GRIN lenses

Cameras

Tissue optics

Hypoxia

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