Robust 4D wavefront control through coherent fiber bundles for lensless endoscopy and optical tweezing (Conference Presentation)

Elias Scharf; Robert Kuschmierz; Jürgen Czarske

doi:10.1117/12.2543213

11 March 2020 Robust 4D wavefront control through coherent fiber bundles for lensless endoscopy and optical tweezing (Conference Presentation)

Elias Scharf, Robert Kuschmierz, Jürgen Czarske

Author Affiliations +

Proceedings Volume 11248, Adaptive Optics and Wavefront Control for Biological Systems VI; 112480T (2020) https://doi.org/10.1117/12.2543213
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We present a fast holographic endoscope with needle footprint. Robustness versus bending is achieved by a single sided self-calibration of the fiber bundle. Incorporating an adaptive lens and 2-axis galvo scanner allows 3D scans with one Mega voxel per second. While the 3D imaging is demonstrated at 3µm fluorescent beads, we also demonstrate the applicability in 2-axis cell rotators by precisely rotating two foci with an angle uncertainty below 1°. For the future, we expect this approach will lead us to create tools for deeper tissue imaging and cell manipulation.

Conference Presentation

Citation Download Citation

Elias Scharf, Robert Kuschmierz, and Jürgen Czarske "Robust 4D wavefront control through coherent fiber bundles for lensless endoscopy and optical tweezing (Conference Presentation)", Proc. SPIE 11248, Adaptive Optics and Wavefront Control for Biological Systems VI, 112480T (11 March 2020); https://doi.org/10.1117/12.2543213

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