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10 March 2020 Nanoplasmonic-enhanced cellular imaging (Conference Presentation)
Frederic A. Banville, Julien Moreau, Jean-François Bryche, Michel Grandbois, Michael T. Canva, Paul G. Charette
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Proceedings Volume 11257, Plasmonics in Biology and Medicine XVII; 1125704 (2020) https://doi.org/10.1117/12.2546529
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
We have demonstrated, numerically and experimentally, that optimized nanostructured plasmonics substrates can generate new hybrid plasmonic modes that possess the spectral dispersion of propagating plasmon but with a much lower propagating length. The imaging performances of these nanostructured SPR chips were recently assessed by studying cellular responses following biochemical stimulation, in particular by real-time monitoring of integrity changes in confluent endothelial cell layer. Improvement in spatial resolution has resulted in an increase in detection sensitivity to cellular activity, with no detectable disturbances in cellular behavior due to the presence of nanostructures.
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Frederic A. Banville, Julien Moreau, Jean-François Bryche, Michel Grandbois, Michael T. Canva, and Paul G. Charette "Nanoplasmonic-enhanced cellular imaging (Conference Presentation)", Proc. SPIE 11257, Plasmonics in Biology and Medicine XVII, 1125704 (10 March 2020); https://doi.org/10.1117/12.2546529
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KEYWORDS
Nanostructuring
Spatial resolution
Surface plasmons
Biology
Cell biology
Metals
Pharmacology
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