Quantitative 3D fluorescence diffuse optical tomography with 3D ultrasound imaging registration in small animal study

Chen-Yu Liu; Shih-Po Su; Pei-An Lo; Hui-Hua Kenny Chiang

doi:10.1117/12.2555445

30 March 2020 Quantitative 3D fluorescence diffuse optical tomography with 3D ultrasound imaging registration in small animal study

Chen-Yu Liu, Shih-Po Su, Pei-An Lo, Hui-Hua Kenny Chiang

Author Affiliations +

Proceedings Volume 11351, Unconventional Optical Imaging II; 113511M (2020) https://doi.org/10.1117/12.2555445
Event: SPIE Photonics Europe, 2020, Online Only

Abstract

An innovative dual-modality 3D fluorescence/3D ultrasound tomography system was demonstrated in this research. The system includes an electron-multiplying charge-coupled device (EMCCD), a 660 nm wavelength fiber-coupling laser, and a 10-15 MHz frequency customized single-element ultrasound transducer on a 3D rotating scanning device. We combined multiple ultrasound images from different sections to obtain a whole-body 3D mesh of mice, which provide anatomical information. In this study, we demonstrated the accuracy of this system through a 4T1 tumor-bearing nude mice experiment.

Conference Presentation

Citation Download Citation

Chen-Yu Liu, Shih-Po Su, Pei-An Lo, and Hui-Hua Kenny Chiang "Quantitative 3D fluorescence diffuse optical tomography with 3D ultrasound imaging registration in small animal study", Proc. SPIE 11351, Unconventional Optical Imaging II, 113511M (30 March 2020); https://doi.org/10.1117/12.2555445

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available