Lesion visibility in phase-contrast breast CT: comparison with histological images

R. Longo; F. Arfelli; S. Donato; D. Bonazza; L. Brombal; A. Contillo; M. A. Cova; P. Delogu; V. Di Trapani; B. Golosio; G. Mettivier; P. Oliva; L. Rigon; A. Taibi; M. Tonutti; G. Tromba; F. Zanconati

doi:10.1117/12.2564202

22 May 2020 Lesion visibility in phase-contrast breast CT: comparison with histological images

R. Longo, F. Arfelli, S. Donato, D. Bonazza, L. Brombal, A. Contillo, M. A. Cova, P. Delogu, V. Di Trapani, B. Golosio, G. Mettivier, P. Oliva, L. Rigon, A. Taibi, M. Tonutti, G. Tromba, F. Zanconati

Author Affiliations +

Proceedings Volume 11513, 15th International Workshop on Breast Imaging (IWBI2020); 115130S (2020) https://doi.org/10.1117/12.2564202
Event: Fifteenth International Workshop on Breast Imaging, 2020, Leuven, Belgium

Abstract

A Phase-Contrast breast CT facility based on a high-resolution CdTe photon-counting detector is under development at Elettra, the Italian Synchrotron Radiation (SR) facility in Trieste. The CT system exploits propagation-based phasecontrast imaging and phase-retrieval algorithm. The voxel size is 57×57×50 μm³ and the delivered MGDs, about 5 mGy, are comparable with clinical breast CT systems. In the present contribution, the comparisons between histological breast cancers and full breast CT images are presented from samples of breast mastectomy. The high resolution of the breast CT images and low noise due to the phase contrast allow a very fine matching between x-ray CT and histology at acceptable delivered doses.

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R. Longo, F. Arfelli, S. Donato, D. Bonazza, L. Brombal, A. Contillo, M. A. Cova, P. Delogu, V. Di Trapani, B. Golosio, G. Mettivier, P. Oliva, L. Rigon, A. Taibi, M. Tonutti, G. Tromba, and F. Zanconati "Lesion visibility in phase-contrast breast CT: comparison with histological images", Proc. SPIE 11513, 15th International Workshop on Breast Imaging (IWBI2020), 115130S (22 May 2020); https://doi.org/10.1117/12.2564202

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