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Regular blood lipid screening is recommended for those suffering from cardiovascular disease (CVD). Current blood lipid measurements require invasive blood draws and lab-based testing. We introduce here shortwave infrared spatial frequency domain imaging (SWIR SFDI) as a non-invasive technique for blood lipid monitoring. We will report results from an analysis of SFDI measurement parameters (spatial frequency, wavelength, etc.) and light propagation models that result in accurate optical properties and chromophore extractions in the SWIR. Additionally, we will present results from a healthy volunteer study of longitudinal postprandial blood lipid changes measured in superficial blood vessels with SWIR SFDI.
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Anahita Pilvar, Matthew Applegate, Mark Pierce, Darren Roblyer, "Shortwave infrared (SWIR) spatial frequency domain imaging (SFDI) for monitoring optical property changes in blood after a high fat meal," Proc. SPIE 11639, Optical Tomography and Spectroscopy of Tissue XIV, 116391A (5 March 2021); https://doi.org/10.1117/12.2577234