Validation of a handheld optical polarization imager for basal cell carcinoma detection

Peter Jermain; Tyler Iorizzo; Bassel Mahmoud; Anna N. Yaroslavsky

doi:10.1117/12.2588586

5 March 2021 Validation of a handheld optical polarization imager for basal cell carcinoma detection

Peter Jermain, Tyler Iorizzo, Bassel Mahmoud, Anna N. Yaroslavsky

Proceedings Volume 11641, Dynamics and Fluctuations in Biomedical Photonics XVIII; 1164104 (2021) https://doi.org/10.1117/12.2588586
Event: SPIE BiOS, 2021, Online Only

Abstract

Skin cancer is the most common human malignancy. The goal of this pilot study was to validate a novel handheld optical polarization imaging (OPI) device for preoperative detection of basal cell carcinoma (BCC) margins. Ten patients with biopsy proven basal cell carcinoma (BCC) were imaged prior to Mohs surgery at UMASS Memorial Medical Center. Preliminary results from analysis of 10 BCC lesions show a strong correlation between optical imaging and histopathology. These findings indicate OPI may be a valuable tool for optimizing surgical treatment of skin cancer.

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Peter Jermain, Tyler Iorizzo, Bassel Mahmoud, and Anna N. Yaroslavsky "Validation of a handheld optical polarization imager for basal cell carcinoma detection", Proc. SPIE 11641, Dynamics and Fluctuations in Biomedical Photonics XVIII, 1164104 (5 March 2021); https://doi.org/10.1117/12.2588586

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