Dual-wavelength fluorescence imaging of chlorin-based photosensitizers

A. V. Khilov; D. A. Kurakina; E. A. Sergeeva; M. A. Shakhova; A. S. Malygina; A. M. Mironycheva; K. G. Pavlova; A. A. Getmanskaya; I. V. Turchin; I. L. Shlivko; S. V. Gamayunov; M. Yu. Kirillin

doi:10.1117/12.2614879

7 December 2021 Dual-wavelength fluorescence imaging of chlorin-based photosensitizers

A. V. Khilov, D. A. Kurakina, E. A. Sergeeva, M. A. Shakhova, A. S. Malygina, A. M. Mironycheva, K. G. Pavlova, A. A. Getmanskaya, I. V. Turchin, I. L. Shlivko, S. V. Gamayunov, M. Yu. Kirillin

Author Affiliations +

Proceedings Volume 11919, Translational Biophotonics: Diagnostics and Therapeutics; 119191N (2021) https://doi.org/10.1117/12.2614879
Event: European Conferences on Biomedical Optics, 2021, Online Only

Abstract

Employment of chlorin-based photosensitizers featuring two peaks in absorption spectrum as drugs for photodynamic therapy allows for dual-wavelength fluorescence imaging providing estimation of photosensitizer localization depth.

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A. V. Khilov, D. A. Kurakina, E. A. Sergeeva, M. A. Shakhova, A. S. Malygina, A. M. Mironycheva, K. G. Pavlova, A. A. Getmanskaya, I. V. Turchin, I. L. Shlivko, S. V. Gamayunov, and M. Yu. Kirillin "Dual-wavelength fluorescence imaging of chlorin-based photosensitizers", Proc. SPIE 11919, Translational Biophotonics: Diagnostics and Therapeutics, 119191N (7 December 2021); https://doi.org/10.1117/12.2614879

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KEYWORDS

Picosecond phenomena

Luminescence

Photodynamic therapy

In vivo imaging

Optical properties

Tissues

Animal model studies

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