Optical skin biopsy using multimodal line-field confocal optical coherence tomography (LC-OCT)

Jonas Ogien; Léna Waszczuk; Mariano Suppa; Véronique del Marmol; Josep Malvehy; Elisa Cinotti; Pietro Rubegni; Jean-Luc Perrot; Arnaud Dubois

doi:10.1117/12.2612808

7 March 2022 Optical skin biopsy using multimodal line-field confocal optical coherence tomography (LC-OCT)

Jonas Ogien, Léna Waszczuk, Mariano Suppa, Véronique del Marmol, Josep Malvehy, Elisa Cinotti, Pietro Rubegni, Jean-Luc Perrot, Arnaud Dubois

Author Affiliations +

Proceedings Volume 11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI; 1194806 (2022) https://doi.org/10.1117/12.2612808
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Line-field confocal optical coherence tomography (LC-OCT) is an imaging technique based on a combination of confocal microscopy and OCT, allowing three-dimensional cellular-resolution imaging of the skin in vivo. We present the latest advances in LC-OCT to facilitate the use of the technique by dermatologists and improve the diagnosis and analysis of skin lesions. A video camera was incorporated into a handheld probe to acquire dermoscopic images in parallel with LCOCT images. A confocal Raman spectrometer was associated with a LC-OCT device to record morphological images of the skin in which points of interest can be subjected to molecular characterization.

Conference Presentation

Citation Download Citation

Jonas Ogien, Léna Waszczuk, Mariano Suppa, Véronique del Marmol, Josep Malvehy, Elisa Cinotti, Pietro Rubegni, Jean-Luc Perrot, and Arnaud Dubois "Optical skin biopsy using multimodal line-field confocal optical coherence tomography (LC-OCT)", Proc. SPIE 11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI, 1194806 (7 March 2022); https://doi.org/10.1117/12.2612808

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