Design and optimization of simulated light delivery systems for photoacoustic assessment of peripheral nerve injury

Michelle T. Graham; Nicholas von Guionneau; Sami Tuffaha; Muyinatu A. Lediju Bell

doi:10.1117/12.2610511

3 March 2022 Design and optimization of simulated light delivery systems for photoacoustic assessment of peripheral nerve injury

Michelle T. Graham, Nicholas von Guionneau, Sami Tuffaha, Muyinatu A. Lediju Bell

Author Affiliations +

Proceedings Volume 11960, Photons Plus Ultrasound: Imaging and Sensing 2022; 1196012 (2022) https://doi.org/10.1117/12.2610511
Event: SPIE BiOS, 2022, San Francisco, California, United States

Conference Poster

Abstract

Precise assessment of nerve injury optimizes outcomes after surgical nerve repair. Photoacoustic imaging is a promising technique for this intraoperative assessment, but is challenged by optical scattering which reduces light penetration into nerve tissue. This work investigates custom light delivery methods to enhance optical penetration into nerve tissue using Monte Carlo simulations. Light sources were positioned in four configurations surrounding the nerve using sparse activation patterns that were evenly distributed or clustered. Results indicate that a custom light delivery system with combined radial and lateral trajectory illumination maximize optical penetration into nerve tissue for intraoperative photoacoustic assessment of nerve injury.

Conference Presentation

Citation Download Citation

Michelle T. Graham, Nicholas von Guionneau, Sami Tuffaha, and Muyinatu A. Lediju Bell "Design and optimization of simulated light delivery systems for photoacoustic assessment of peripheral nerve injury", Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 1196012 (3 March 2022); https://doi.org/10.1117/12.2610511

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