Evaluation of the timing performance of silicon photomultiplier detectors array and its preliminary application in fluorescence lifetime sensing and diffuse optics

E. Avanzi; A. Ghezzi; A. Farina; C. D'Andrea; A. Dalla Mora; L. Di Sieno

doi:10.1117/12.2648786

7 March 2023 Evaluation of the timing performance of silicon photomultiplier detectors array and its preliminary application in fluorescence lifetime sensing and diffuse optics

E. Avanzi, A. Ghezzi, A. Farina, C. D'Andrea, A. Dalla Mora, L. Di Sieno

Author Affiliations +

Proceedings Volume 12376, Optical Tomography and Spectroscopy of Tissue XV; 123760N (2023) https://doi.org/10.1117/12.2648786
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

By exploiting the recent components miniaturization trend, we realize a small and cheap multifunctional time-resolved (TR) single-photon detection chain. It is based on 16 channels, which can be configured either as 16 independently located channels for TR diffuse optical tomography or as a linear array for parallel TR fluorescence spectroscopy. Both applications require a detector with high time resolution and high light harvesting capability (i.e., large active area and detection efficiency). Thus, each detection channel contains a 1.3 x 1.3 mm2 active area silicon photomultiplier and its home-made electronics specifically designed for avalanche sensing and amplification, capable of optimizing the single-photon timing resolution despite the miniaturization. In this study we describe the timing performances of a first 8- channel prototype and its first application in fluorescence lifetime sensing. Then, we show the capability of the whole 16-channel array in detecting absorption changes within a homogeneous scattering medium. We have been able to obtain a single-photon timing resolution of almost 60 ps, that is close to the best ever achieved with this kind of detector. For the validation in fluorescence lifetime sensing, the fluorescence signal acquired by the proposed prototype is comparable to the one obtained using a state-of-the-art setup based on a PMT detector. In the validation in diffuse optics, we clearly detected the absorption perturbation. This confirms the suitability of this stackable solid-state detector array for both applications.

Conference Presentation

Citation Download Citation

E. Avanzi, A. Ghezzi, A. Farina, C. D'Andrea, A. Dalla Mora, and L. Di Sieno "Evaluation of the timing performance of silicon photomultiplier detectors array and its preliminary application in fluorescence lifetime sensing and diffuse optics", Proc. SPIE 12376, Optical Tomography and Spectroscopy of Tissue XV, 123760N (7 March 2023); https://doi.org/10.1117/12.2648786

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