Custom: terminated multimode fibre probe for holographic micro-endoscopy

Miroslav Stibůrek; Petr Jákl; Tomáš Pikálek; Petra Ondráčková; Tomáš Čižmár

doi:10.1117/12.2664219

12 December 2022 Custom: terminated multimode fibre probe for holographic micro-endoscopy

Miroslav Stibůrek, Petr Jákl, Tomáš Pikálek, Petra Ondráčková, Tomáš Čižmár

Proceedings Volume 12502, 22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics; 1250211 (2022) https://doi.org/10.1117/12.2664219
Event: 22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics, 2022, Wojanow, Poland

Abstract

Using multiphoton microscopy, we can image the tissue with sub-cellular resolution at depths down to 1.5 mm. Beyond this reach, the light must be delivered to the target region by optical relay elements inserted into the tissue – the endoscopes. Focusing light through a step-index multimode optical fibre (MMF) using wave-front control enables minimally-invasive endoscopy. With fibre micro-endoscopes, we can reach any depth with negligible tissue disruption and keep the resolution below 1 micrometre, sufficient for in vivo microscopy. We designed a novel custom-terminated multimode fibre probe. This work will focus on optical fibre probe manufacturing methods (etching, polishing and coating) and their impact on imaging quality.

Citation Download Citation

Miroslav Stibůrek, Petr Jákl, Tomáš Pikálek, Petra Ondráčková, and Tomáš Čižmár "Custom: terminated multimode fibre probe for holographic micro-endoscopy", Proc. SPIE 12502, 22nd Polish-Slovak-Czech Optical Conference on Wave and Quantum Aspects of Contemporary Optics, 1250211 (12 December 2022); https://doi.org/10.1117/12.2664219

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