Design and optimization of injection needle for digital PCR detector

Peiqi Zhang; Dongmei Li

doi:10.1117/12.2671907

28 February 2023 Design and optimization of injection needle for digital PCR detector

Peiqi Zhang, Dongmei Li

Proceedings Volume 12596, International Conference on Mechatronics Engineering and Artificial Intelligence (MEAI 2022); 1259608 (2023) https://doi.org/10.1117/12.2671907
Event: International Conference on Mechatronics Engineering and Artificial Intelligence (MEAI 2022), 2022, Changsha, China

Abstract

In order to meet the automatic injection and cleaning functions of digital PCR detector, a double-layer injection needle and its liquid path device were designed. Firstly, the finite element analysis of the injection needle was carried out based on ANSYS Workbench. Combined with the theoretical calculation, it is found that the stability is poor and the bending stiffness is insufficient. Then, to solve this problem, a spiral spring was added between the inner needle and the outer tube to optimize the injection needle, and the influence of spring position, length and pitch on the deformation of the injection needle was explored. Finally, considering the strength, deformation and cleaning effect, it is determined that the best scheme is that the spring is 5mm from the outlet of the outer tube, the length is 5mm and the pitch is 1mm. At this time, the maximum deformation caused by 0.1N lateral force is reduced from 0.527mm to 0.158mm, the maximum stress is reduced from 151.5MPa to 86.25MPa and the critical buckling pressure is increased from 4.276N to 28.468N. After optimization, the strength, stiffness and stability of the injection needle are guaranteed. The research results are of great significance to the design and optimization of the injection needle.

Citation Download Citation

Peiqi Zhang and Dongmei Li "Design and optimization of injection needle for digital PCR detector", Proc. SPIE 12596, International Conference on Mechatronics Engineering and Artificial Intelligence (MEAI 2022), 1259608 (28 February 2023); https://doi.org/10.1117/12.2671907

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available