An integrated fixation and stimulus channel for adaptive optics ophthalmoscopy with a large working distance, steering field, dioptric range, and light efficiency

Yan Liu; Marcel T. Bernucci; Qiuzhi Ji; James A. Crowell; Kristen Bowles-Johnson; Matthew J. Keller; Donald T. Miller

doi:10.1117/12.3003262

12 March 2024 An integrated fixation and stimulus channel for adaptive optics ophthalmoscopy with a large working distance, steering field, dioptric range, and light efficiency

Yan Liu, Marcel T. Bernucci, Qiuzhi Ji, James A. Crowell, Kristen Bowles-Johnson, Matthew J. Keller, Donald T. Miller

Author Affiliations +

Proceedings Volume 12824, Ophthalmic Technologies XXXIV; 1282402 (2024) https://doi.org/10.1117/12.3003262
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Adaptive optics (AO) ophthalmoscopes enable retinal imaging at cellular resolution. The small field of view (FOV) and high magnification of these instruments make inclusion of a fixation channel critical for controlling the patch of retina that is stimulated with light and imaged. Here, we develop a more powerful fixation channel that is integrated with an improved stimulus channel in the Indiana AO optical coherence tomography (AO-OCT) system. It uses all stock components except one 3D printed optical mount and some machined adaptor plates. We balanced the trade-offs between subject working distance, steering field of view, dioptric correction range, and stimulus light efficiency and achieved better performance in all areas compared to our previous channel. We report on the overarching objectives of the integrated fixation and stimulus channel, its design and its validation as illustrated by several AO-OCT imaging examples. While intended for our AO-OCT system, the design, components, and performance trade-offs are general enough to be applicable to many other AO ophthalmoscopes in the field.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Yan Liu, Marcel T. Bernucci, Qiuzhi Ji, James A. Crowell, Kristen Bowles-Johnson, Matthew J. Keller, and Donald T. Miller "An integrated fixation and stimulus channel for adaptive optics ophthalmoscopy with a large working distance, steering field, dioptric range, and light efficiency", Proc. SPIE 12824, Ophthalmic Technologies XXXIV, 1282402 (12 March 2024); https://doi.org/10.1117/12.3003262

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