Polarized light imaging sensitive to 100 to 300nm size range of light-scattering tissue structure

Steven L. Jacques

doi:10.1117/12.3014183

15 March 2024 Polarized light imaging sensitive to 100 to 300nm size range of light-scattering tissue structure

Steven L. Jacques

Proceedings Volume 12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis; 1283603 (2024) https://doi.org/10.1117/12.3014183
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

The polarization (Q = co-polarized - cross-polarized) of reflectance from a tissue of incident linearly polarized light serves as a gate that isolates superficially scattered light, rejecting multiply scattered diffuse light. Pathology often arises in superficial tissue layers. But to interpret an observed change in Q in the field of view, one must decide: ”Is the change due to an altered size of scatterers or to an altered concentration of scatterers?” This study uses the GPU-accelerated MCX version of Monte Carlo polarized light transport, based on light-scattering Mie spheres of varying size, to answer this question.

Conference Presentation

Citation Download Citation

Steven L. Jacques "Polarized light imaging sensitive to 100 to 300nm size range of light-scattering tissue structure", Proc. SPIE 12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis, 1283603 (15 March 2024); https://doi.org/10.1117/12.3014183

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