Integrative pathophysiological and correlation-optical study of the kidneys for the formation of tubulo-interstitial syndrome: part 1–polarization and birefringence structure

Yurii Rohovyi; Vitalyi Savka; Vyacheslav Bilookyi; Michael Sheremet; Andrii Bocharov; Kateryna Pryimak; Oleksandr Bilookyi

doi:10.1117/12.3014077

5 January 2024 Integrative pathophysiological and correlation-optical study of the kidneys for the formation of tubulo-interstitial syndrome: part 1–polarization and birefringence structure

Yurii Rohovyi, Vitalyi Savka, Vyacheslav Bilookyi, Michael Sheremet, Andrii Bocharov, Kateryna Pryimak, Oleksandr Bilookyi

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Proceedings Volume 12938, Sixteenth International Conference on Correlation Optics; 129381I (2024) https://doi.org/10.1117/12.3014077
Event: International Conference Correlation Optics (COR 2023), 2023, Chernivtsi, Ukraine

Abstract

In experiments on 32 white nonlinear male rats weighing 0.16-0.18 kg on a hyposodium diet, the diagnostic possibilities of integrative correlation-optical study of the cortex, medullary area and papilla of the kidneys compared to the functional and biochemical state of the kidneys during the formation tubulo-interstitial syndrome on the 30th day of the polyuric stage of sublimate nephropathy. The formation of tubulo-interstitial syndrome showed the greatest increase in the average phase shift of the crystalline substance in the papilla of the kidneys in 7.44 times, in second place increased the excess orientation of the crystalline substance in the renal cortex by 6.73 times in third place asymmetry of phase shift medullary area of the kidneys 6.07 times, which were much more sensitive than the study of functional and biochemical state of the kidneys in the formation of tubulo-interstitial syndrome with inhibition of succinate dehydrogenase activity in the renal cortex of the kidneys 3.60 times, in second place was an increase in oxyproline in the renal cortex as a marker of collagenogenesis in2,03 times and in third place inhibition of fibrinolytic activity of urine by 1.84 times.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

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Yurii Rohovyi, Vitalyi Savka, Vyacheslav Bilookyi, Michael Sheremet, Andrii Bocharov, Kateryna Pryimak, and Oleksandr Bilookyi "Integrative pathophysiological and correlation-optical study of the kidneys for the formation of tubulo-interstitial syndrome: part 1–polarization and birefringence structure", Proc. SPIE 12938, Sixteenth International Conference on Correlation Optics, 129381I (5 January 2024); https://doi.org/10.1117/12.3014077

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KEYWORDS

Kidney

Crystals

Birefringence

Chromium

Sodium

Blood

Crystallography

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