Metalens-based optical coherence tomography for high-resolution biomedical imaging

Abdul Jabbar; Isma Javed; Azhar Javed Satti; Humberto Cabrera; Nasir Mahmood; Muhammad Qasim Mehmood

doi:10.1117/12.3022174

24 June 2024 Metalens-based optical coherence tomography for high-resolution biomedical imaging

Abdul Jabbar, Isma Javed, Azhar Javed Satti, Humberto Cabrera, Nasir Mahmood, Muhammad Qasim Mehmood

Proceedings Volume 13020, Advances in Optical Thin Films VIII; 1302015 (2024) https://doi.org/10.1117/12.3022174
Event: SPIE Optical Systems Design, 2024, Strasbourg, France

Conference Poster

Abstract

The American Society of Cancer reports an annual average of 240,000 breast cancer diagnoses in the USA, resulting in approximately 42,000 women and 500 men succumbing to the disease each year. The conventional diagnosis of critical diseases like breast cancer, lung cancer, and skin cancer frequently necessitates invasive biopsy procedures, which involve the removal of a tissue sample for diagnostic analysis, potentially posing infection risks. However, conventional Optical Coherence Tomography (OCT) has emerged as a non-invasive imaging technique that mitigates these risks by generating cross-sectional biological sample images through the principles of light scattering and reflection. Although conventional OCT excels in its depth of focus, it faces challenges related to limited lateral resolution and diffraction constraints. Consequently, we propose a metalens-based OCT for high-resolution biomedical tissue imaging. Metalens-based OCT achieves optical system miniaturization by replacing traditional bulky lenses. The metalens is designed on a crystalline silicon dioxide (SiO₂) substrate with a 490 nm unit cell periodicity. Its dimensions are 380 nm in length, 185 nm in width, and 1100 nm in height. The suggested metalens operates in the 1300–1570 nm wavelength range and has over 65% transmission to provide improved depth of focus and lateral resolution. Simulated results indicate that metalens depth of focus and full-width half maximum approach 260 and 125 μm, respectively. Hence, our metalens proposal, offering high resolution and an increased depth of field, presents a viable choice for surgical and in vivo endoscopy imaging applications.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Abdul Jabbar, Isma Javed, Azhar Javed Satti, Humberto Cabrera, Nasir Mahmood, and Muhammad Qasim Mehmood "Metalens-based optical coherence tomography for high-resolution biomedical imaging", Proc. SPIE 13020, Advances in Optical Thin Films VIII, 1302015 (24 June 2024); https://doi.org/10.1117/12.3022174

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