Irving J. Bigio,1 Thomas R. Loree,1 Judith R. Mourant,1 Tsutomu Shimada,1 K. Story-Held,2 Randolph D. Glickmanhttps://orcid.org/0000-0001-6081-5410,3 Richard L. Conn4
1Los Alamos National Lab. (United States) 2Univ. of Texas Health Sciences Ctr. (United States) 3Univ. of Texas (United States) 4Lovelace Medical Ctr. (United States)
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
A non-invasive diagnostic tool that could identify malignancy in situ and in real time would have a major impact on the detection and treatment of cancer. We have developed and are testing early prototypes of an optical biopsy system (OBS) for detection of cancer and other tissue pathologies. The OBS invokes a unique approach to optical diagnosis of tissue pathologies based on the elastic scattering properties, over a wide range of wavelengths, of the microscopic structure of the tissue. In addition to the reduced invasiveness of this technique compared with current state-of-the-art methods (surgical biopsy and pathology analysis), the OBS offers the possibility of impressively faster diagnostic assessment.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Irving J. Bigio, Thomas R. Loree, Judith R. Mourant, Tsutomu Shimada, K. Story-Held, Randolph D. Glickman, Richard L. Conn, "Optical diagnostics based on elastic scattering: recent clinical demonstrations with the Los Alamos optical biopsy system," Proc. SPIE 2081, Optical Biopsy, (15 January 1994); https://doi.org/10.1117/12.166823