Noninvasive tissue fluorescence study of a fluorescent dye (calcein) on intraperitoneal glucose administration

Jean-Marie Devoisselle; Serge R. Mordon; Sylvie Soulie-Begu

doi:10.1117/12.198714

4 January 1995 Noninvasive tissue fluorescence study of a fluorescent dye (calcein) on intraperitoneal glucose administration

Jean-Marie Devoisselle, Serge R. Mordon, Sylvie Soulie-Begu

Author Affiliations +

Proceedings Volume 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging; (1995) https://doi.org/10.1117/12.198714
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

The diagnostic exploitation of fluorescence spectroscopy and imaging has been largely used in experimental and clinical oncology. Only a few studies concern the ability of these techniques to study the in vivo behavior of fluorescent drugs or dyes. We have proposed recently a spectroscopic and imaging method to monitor pH in living tissues using pH-sensitive dyes. The tumor pH was depressed by previous glucose injection. We describe in this study the effect of glucose injection on the pharmacokinetic behavior of a fluorescent dye (calcein) by noninvasive fluorescence spectroscopy.

Citation Download Citation

Jean-Marie Devoisselle, Serge R. Mordon, and Sylvie Soulie-Begu "Noninvasive tissue fluorescence study of a fluorescent dye (calcein) on intraperitoneal glucose administration", Proc. SPIE 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging, (4 January 1995); https://doi.org/10.1117/12.198714

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available