Effects of Er:YAG lasers of different pulse widths on rabbit corneas

Jing-cai Lian; Kang-sun Wang M.D.

doi:10.1117/12.209829

22 May 1995 Effects of Er:YAG lasers of different pulse widths on rabbit corneas

Jing-cai Lian, Kang-sun Wang M.D.

Proceedings Volume 2393, Ophthalmic Technologies V; (1995) https://doi.org/10.1117/12.209829
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

Photorefractive keratectomy with 193 nm excimer laser has been used for the treatment of myopia. Because of its big size and hazards of toxic gas, a 2.94 micrometers Er:YAG laser had been suggested for this purpose. The aims of the present study was to investigate the thermal effects in the corneas after exposed to Er:YAG laser with different pulse widths. 14 New- Zealand white rabbits were divided into two groups. In the first group, the corneas were irradiated by a normal spiking mode Er:YAG laser with a pulse width of 150 microsecond(s) at the fluence of 585 approximately 697 mJ/cm². In the second group, the corneas were exposed to a Q-switch mode of Er:YAG laser with a pulse width of 700 ns at the fluence of 524 approximately 562 mJ/cm² and 700 approximately 850 mJ/cm². The eyes were followed up 5 months and enucleated for histopathologic inspection 30 minutes, 2 weeks, 1, 2 and 5 months postoperatively. Corneal stromal hazes in the first group were more obvious than that in the second group. The most significant haze was observed two weeks after treatments and disappeared at two months. The adjacent thermal damage in the first group were much wider than that in the second group. To minimize the thermal and shock wave effect, the Q-switch mode Er:YAG laser with pulse width around 700 ns is recommended for corneal surgery.

Citation Download Citation

Jing-cai Lian and Kang-sun Wang M.D. "Effects of Er:YAG lasers of different pulse widths on rabbit corneas", Proc. SPIE 2393, Ophthalmic Technologies V, (22 May 1995); https://doi.org/10.1117/12.209829

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