Practical nonlinear method for detection of respiratory and cardiac dysfunction in human subjects

Richard A. Katz; Michael S. Lawee; Anthony Kief Newman; J. Woodrow Weiss; Shalabh Chandra; Richard A. Grimm; James D. Thomas

doi:10.1117/12.227899

1 December 1995 Practical nonlinear method for detection of respiratory and cardiac dysfunction in human subjects

Richard A. Katz, Michael S. Lawee, Anthony Kief Newman, J. Woodrow Weiss, Shalabh Chandra, Richard A. Grimm, James D. Thomas

Author Affiliations +

Proceedings Volume 2612, Chaotic Circuits for Communication; (1995) https://doi.org/10.1117/12.227899
Event: Photonics East '95, 1995, Philadelphia, PA, United States

Abstract

This research applies novel nonlinear signal detection techniques in studies of human subjects with respiratory and cardiac diseases. One of the studies concerns a breathing disorder during sleep, a disease called Obstructive Sleep Apnea (OSA). In a second study we investigate a disease of the heart, Atrial Fibrillation (AF). The former study involves nonlinear processing of the time sequences of sleep apnea recordings (cardio-respirograms) collected from patients with known obstructive sleep apnea, and from a normal control. In the latter study, we apply similar nonlinear metrics to Doppler flow measurements obtained by transesophageal echocardiography (TEE). One of our metrics, the 'chaotic radius' is used for tracking the position of points in phase space relative to some reference position. A second metric, the 'differential radius' provides a measure of the separation rate of contiguous (evolving) points in phase space. A third metric, the 'chaotic frequency' gives angular position of the phase space orbit as a function of time. All are useful for identifying change of physiologic condition that is not always apparent using conventional methods.

Citation Download Citation

Richard A. Katz, Michael S. Lawee, Anthony Kief Newman, J. Woodrow Weiss, Shalabh Chandra, Richard A. Grimm, and James D. Thomas "Practical nonlinear method for detection of respiratory and cardiac dysfunction in human subjects", Proc. SPIE 2612, Chaotic Circuits for Communication, (1 December 1995); https://doi.org/10.1117/12.227899

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