Foveal cone mosaic imaged in vivo by an objective high-resolution technique

Susana Celestino Marcos; Rafael Fonolla Navarro; Pablo Artal

doi:10.1117/12.229572

10 January 1996 Foveal cone mosaic imaged in vivo by an objective high-resolution technique

Susana Celestino Marcos, Rafael Fonolla Navarro, Pablo Artal

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Proceedings Volume 2632, Lasers in Ophthalmology III; (1996) https://doi.org/10.1117/12.229572
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

We have developed a new technique for the objective determination of the cone spacing in the living human fovea, and obtained direct measurements of the distance between cones at retinal eccentricities ranging from 0 to 1 deg. The method is similar to stellar speckle interferometry, and consists of recording a series of short-exposure images of small foveal patches, illuminated by a laser spot. Each individual image presents a speckle pattern, correlated with the topography of the cone mosaic, and contains spatial frequency information up to the diffraction limit of the optical system of the eye. The cone spacing is measured in the spatial domain, as the reciprocal of the radius of the ring present in the average power spectrum. The results obtained are in close agreement with estimates based on microscopy of excised fovea, with psychophysical measurements, and with recent results obtained with another high resolution imaging technique outside the center of the fovea.

Citation Download Citation

Susana Celestino Marcos, Rafael Fonolla Navarro, and Pablo Artal "Foveal cone mosaic imaged in vivo by an objective high-resolution technique", Proc. SPIE 2632, Lasers in Ophthalmology III, (10 January 1996); https://doi.org/10.1117/12.229572

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KEYWORDS

Cones

Eye

Spatial frequencies

In vivo imaging

Speckle pattern

Speckle interferometry

Diffraction

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