Image-guided MR spectroscopy VOI localization for longitudinal studies

Steven L. Hartmann; Benoit M. Dawant; Mitchell H. Parks M.D.; Heide Schlack; Peter R. Martin

doi:10.1117/12.310916

24 June 1998 Image-guided MR spectroscopy VOI localization for longitudinal studies

Steven L. Hartmann, Benoit M. Dawant, Mitchell H. Parks M.D., Heide Schlack, Peter R. Martin

Proceedings Volume 3338, Medical Imaging 1998: Image Processing; (1998) https://doi.org/10.1117/12.310916
Event: Medical Imaging '98, 1998, San Diego, CA, United States

Abstract

Longitudinal magnetic resonance spectroscopy (MRS) studies require accurate repositioning of the volume of interest (VOI) over which measurements are made. In this work we present and evaluate a method for the image-guided repositioning of brain volumes of interest. The point-based registration technique we developed allows the repositioning to be performed on-line (i.e., while the patient is in the scanner). MR image volumes were acquired from six subjects, three scans each over the course of a month. During the first scan, two spectroscopy VOIs are visually selected: one in the frontal white matter, the other in the superior cerebellar vermis. The coordinates of 13 internal brain landmarks were also identified. During both subsequent scans, the same 13 landmarks were also identified, and the transformation that registers the first set of landmarks to the subsequent set is compared. This result is used to automatically map the position of the spectroscopy. VOIs from the first volume to the current volume. For the six subjects evaluated to date, we show an average repositioning error of the spectroscopy VOIs in the order of 1 mm. This accuracy allows us to conclude that any variation in the MR spectra are unlikely to be due to repositioning error.

Citation Download Citation

Steven L. Hartmann, Benoit M. Dawant, Mitchell H. Parks M.D., Heide Schlack, and Peter R. Martin "Image-guided MR spectroscopy VOI localization for longitudinal studies", Proc. SPIE 3338, Medical Imaging 1998: Image Processing, (24 June 1998); https://doi.org/10.1117/12.310916

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available