Improved low-power semiconductor diode lasers for photodynamic therapy in veterinary medicine

Susanne M. Lee; Eduard K. Mueller; Brian C. Van de Workeen; Otward M. Mueller

doi:10.1117/12.427770

21 May 2001 Improved low-power semiconductor diode lasers for photodynamic therapy in veterinary medicine

Susanne M. Lee, Eduard K. Mueller, Brian C. Van de Workeen, Otward M. Mueller

Proceedings Volume 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI; (2001) https://doi.org/10.1117/12.427770
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Cryogenically cooling semiconductor diode lasers provides higher power output, longer device lifetime, and greater monochromaticity. While these effects are well known, such improvements have not been quantified, and thus cryogenically operated semiconductor lasers have not been utilized in photodynamic therapy (PDT). We report quantification of these results from laser power meter and photospectrometer data. The emission wavelengths of these low power multiple quantum well semiconductor lasers were found to decrease and become more monochromatic with decreasing temperature. Significant power output improvements also were obtained at cryogenic temperatures. In addition, the threshold current, i.e. the current at which lasing begins, decreased with decreasing temperature. This lower threshold current combined with the increased power output produced dramatically higher device efficiencies. It is proposed that cryogenic operation of semiconductor diode lasers will reduce the number of devices needed to produce the requisite output for many veterinary and medical applications, permitting significant cost reductions.

Citation Download Citation

Susanne M. Lee, Eduard K. Mueller, Brian C. Van de Workeen, and Otward M. Mueller "Improved low-power semiconductor diode lasers for photodynamic therapy in veterinary medicine", Proc. SPIE 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI, (21 May 2001); https://doi.org/10.1117/12.427770

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