Experimental tests of a two-layer Monte Carlo-diffusion hybrid model for photon migration in the frequency domain

Gregory W. Faris; George Alexandrakis; David R. Busch; Michael S. Patterson

doi:10.1117/12.434504

29 June 2001 Experimental tests of a two-layer Monte Carlo-diffusion hybrid model for photon migration in the frequency domain

Gregory W. Faris, George Alexandrakis, David R. Busch, Michael S. Patterson

Author Affiliations +

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434504
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

We examine the ability to recover the optical properties of a two-layer turbid medium using multi-distance frequency domain reflectance measurements and a hybrid Monte Carlo-- diffusion model. Frequency domain measurements are performed on two-layer liquid tissue phantoms simulating skin on muscle and skin on fat. Particular care to systematic effects in the photomultiplier is required for the measurements at short source-detectors distances. The model converges when fitting five free parameters (the optical properties of the upper and lower layers and the upper layer thickness). However, discrepancies between experimental and model yield insufficient accuracy for the absorption coefficient of the upper layer.

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Gregory W. Faris, George Alexandrakis, David R. Busch, and Michael S. Patterson "Experimental tests of a two-layer Monte Carlo-diffusion hybrid model for photon migration in the frequency domain", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434504

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