Novel diagnostic method for the detection of far-red fluorescence emission from several tumor-seeking photosensitizers

Theodossis Theodossiou; Vladimir A. Hovhannisyan; P. Kastaniotis; Konstantine Politopoulos; Dido M. Yova

doi:10.1117/12.446511

26 October 2001 Novel diagnostic method for the detection of far-red fluorescence emission from several tumor-seeking photosensitizers

Theodossis Theodossiou, Vladimir A. Hovhannisyan, P. Kastaniotis, Konstantine Politopoulos, Dido M. Yova

Author Affiliations +

Proceedings Volume 4433, Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy; (2001) https://doi.org/10.1117/12.446511
Event: European Conferences on Biomedical Optics, 2001, Munich, Germany

Abstract

A novel detection method for malignant tumour detection through specific accumulation of far-red emitting photosensitisers, has been developed. The set-up, based on He-Ne (633 nm) excitation was tested with phantom malignancies models using photosensitisers on chicken tissue. Intensity vs. depth of tissue measurements as well as photobleaching measurements were performed. Point by point fluorescence imaging indicated that the formation size is not significantly distorted with respect to depth of location.

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Theodossis Theodossiou, Vladimir A. Hovhannisyan, P. Kastaniotis, Konstantine Politopoulos, and Dido M. Yova "Novel diagnostic method for the detection of far-red fluorescence emission from several tumor-seeking photosensitizers", Proc. SPIE 4433, Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy, (26 October 2001); https://doi.org/10.1117/12.446511

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