Optical fibers for improved light delivery in photodynamic therapy and diagnosis

Bolesh J. Skutnik; Wolfgang Neuberger; Stefan Spaniol

doi:10.1117/12.529489

14 June 2004 Optical fibers for improved light delivery in photodynamic therapy and diagnosis

Bolesh J. Skutnik, Wolfgang Neuberger, Stefan Spaniol

Author Affiliations +

Proceedings Volume 5315, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIII; (2004) https://doi.org/10.1117/12.529489
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

For most Photodynamic Therapy (PDT) applications a diffuse, broad and uniform source of irradiation is needed to obtain the most effective and consistent treatment. Since many treatments are within the patient's body, an effective compact fiber optic delivery system is needed for the activation of the photsensitizer drub at the site of the tissue to be treated. High Numerical Aperture (NA) optical fibers have benefits for PDT treatments but possibly even more so for PDT diagnostic applications These are summarized and new optical fibers with high and ultra high NAs are described. Properties of these fibers are presented as well as advantages they have over other fibers for delivering light in various PDT applications. Silica fibers with enhanced effective NAs approaching 0.6 are described.

Citation Download Citation

Bolesh J. Skutnik, Wolfgang Neuberger, and Stefan Spaniol "Optical fibers for improved light delivery in photodynamic therapy and diagnosis", Proc. SPIE 5315, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIII, (14 June 2004); https://doi.org/10.1117/12.529489

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE