Advanced time-correlated single photon counting technique for spectroscopy and imaging of biological systems

Wolfgang Becker; Axel Bergmann; Michal Kacprzak; Adam Liebert

doi:10.1117/12.710872

27 October 2006 Advanced time-correlated single photon counting technique for spectroscopy and imaging of biological systems

Wolfgang Becker, Axel Bergmann, Michal Kacprzak, Adam Liebert

Author Affiliations +

Proceedings Volume 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine; 604714 (2006) https://doi.org/10.1117/12.710872
Event: Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2005, Tianjin, China

Abstract

We present a multi-dimensional TCSPC technique that simultaneously records the photon distribution over the time in the fluorescence decay, the wavelength, and the coordinates of a two-dimensional scan or the time since the start of the experiment. We demonstrate the application of the technique to diffuse optical tomography, single-point autofluorescence measurements of skin, and multi-spectra autofluorescence lifetime imaging of tissue.

Citation Download Citation

Wolfgang Becker, Axel Bergmann, Michal Kacprzak, and Adam Liebert "Advanced time-correlated single photon counting technique for spectroscopy and imaging of biological systems", Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604714 (27 October 2006); https://doi.org/10.1117/12.710872

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