Paper
19 February 2009 Microflow cytometer
Frances S. Ligler, Jeffrey S. Erickson, Joel P. Golden, Jason S. Kim, Mansoor Nasir, Peter J. Howell Jr., Abel L. Thangawng, Lisa Hilliard, George P. Anderson
Author Affiliations +
Abstract
A multi-analyte diagnostic system based on a novel microflow cytometer is under development as a portable, fielddeployable sensor for environmental monitoring and for rapid point-of-care and on-site diagnosis of exposure to biothreat agents. The technology relies on a unique method for ensheathing a sample stream in continuous flow past an illuminated interrogation region. This sheathing approach efficiently focuses particles in the interrogation region of the fluidic channel and minimizes clogging by complex samples. Fluorescently coded microspheres provide the capability for highly multiplexed assays. In this report, separation of six microsphere sets was demonstrated with determination of immunoassays on three of the six sets; comparison to the commercial platform was made.
© (2009) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Frances S. Ligler, Jeffrey S. Erickson, Joel P. Golden, Jason S. Kim, Mansoor Nasir, Peter J. Howell Jr., Abel L. Thangawng, Lisa Hilliard, and George P. Anderson "Microflow cytometer", Proc. SPIE 7167, Frontiers in Pathogen Detection: From Nanosensors to Systems, 71670N (19 February 2009); https://doi.org/10.1117/12.807671
Lens.org Logo
CITATIONS
Cited by 1 scholarly publication.
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Optical fibers

Microfluidics

Luminescence

Particles

Diagnostics

Lithography

Multiplexing

Back to Top