Fiber bundle based fluorescence tomography system for human breast imaging

Yuting Lin; Orhan Nalcioglu; Gultekin Gulsen

doi:10.1117/12.831770

9 July 2009 Fiber bundle based fluorescence tomography system for human breast imaging

Yuting Lin, Orhan Nalcioglu, Gultekin Gulsen

Proceedings Volume 7371, Novel Optical Instrumentation for Biomedical Applications IV; 737108 (2009) https://doi.org/10.1117/12.831770
Event: European Conferences on Biomedical Optics, 2009, Munich, Germany

Abstract

Fluorescence diffuse optical tomography (FT) is a promising molecular imaging technique that can spatially resolve both fluorophore concentration and lifetime parameters. In this phantom study, we built a photo-multiplier tube (PMT) based single detection system that uses fiber bundles to collect light. Measurements were acquired both with a 1 mm diameter single fiber and a 6 mm diameter fiber bundle using the very same detection unit for comparison purposes. We demonstratethat the fluorescence concentration and lifetime can be well recovered for 6 mm diameter objects deeply embedded in an 80 mm diameter breast-sized phantom when the fiber bundle is utilized.

Citation Download Citation

Yuting Lin, Orhan Nalcioglu, and Gultekin Gulsen "Fiber bundle based fluorescence tomography system for human breast imaging", Proc. SPIE 7371, Novel Optical Instrumentation for Biomedical Applications IV, 737108 (9 July 2009); https://doi.org/10.1117/12.831770

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available