Effect of spatial noise of medical grade Liquid Crystal Displays (LCD) on the detection of micro-calcification

Hans Roehrig; Jiahua Fan; William J. Dallas; Elizabeth A. Krupinski; Jeffrey Johnson

doi:10.1117/12.830043

11 September 2009 Effect of spatial noise of medical grade Liquid Crystal Displays (LCD) on the detection of micro-calcification

Hans Roehrig, Jiahua Fan, William J. Dallas, Elizabeth A. Krupinski, Jeffrey Johnson

Author Affiliations +

Proceedings Volume 7450, Penetrating Radiation Systems and Applications X; 74500G (2009) https://doi.org/10.1117/12.830043
Event: SPIE Optical Engineering + Applications, 2009, San Diego, California, United States

Abstract

This presentation describes work in progress that is the result of an NIH SBIR Phase 1 project that addresses the wide- spread concern for the large number of breast-cancers and cancer victims [1,2]. The primary goal of the project is to increase the detection rate of microcalcifications as a result of the decrease of spatial noise of the LCDs used to display the mammograms [3,4]. Noise reduction is to be accomplished with the aid of a high performance CCD camera and subsequent application of local-mean equalization and error diffusion [5,6]. A second goal of the project is the actual detection of breast cancer. Contrary to the approach to mammography, where the mammograms typically have a pixel matrix of approximately 1900 x 2300 pixels, otherwise known as FFDM or Full-Field Digital Mammograms, we will only use sections of mammograms with a pixel matrix of 256 x 256 pixels. This is because at this time, reduction of spatial noise on an LCD can only be done on relatively small areas like 256 x 256 pixels. In addition, judging the efficacy for detection of breast cancer will be done using two methods: One is a conventional ROC study [7], the other is a vision model developed over several years starting at the Sarnoff Research Center and continuing at the Siemens Corporate Research in Princeton NJ [8].

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Hans Roehrig, Jiahua Fan, William J. Dallas, Elizabeth A. Krupinski, and Jeffrey Johnson "Effect of spatial noise of medical grade Liquid Crystal Displays (LCD) on the detection of micro-calcification", Proc. SPIE 7450, Penetrating Radiation Systems and Applications X, 74500G (11 September 2009); https://doi.org/10.1117/12.830043

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KEYWORDS

LCDs

Mammography

Signal to noise ratio

Breast cancer

Quantization

CCD cameras

Statistical analysis

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