Bacterial biofilm disruption using laser-generated shockwaves

Artemio Navarro; Zachary D. Taylor; Anthony Z. Matolek; Ahuva Weltman; Vidyunmala Ramaprasad; Sean Huang; David O. Beenhouwer; David A. Haake; Vijay Gupta; Warren S. Grundfest

doi:10.1117/12.908661

28 February 2012 Bacterial biofilm disruption using laser-generated shockwaves

Artemio Navarro, Zachary D. Taylor, Anthony Z. Matolek, Ahuva Weltman, Vidyunmala Ramaprasad, Sean Huang, David O. Beenhouwer, David A. Haake, Vijay Gupta, Warren S. Grundfest

Author Affiliations +

Proceedings Volume 8214, Advanced Biomedical and Clinical Diagnostic Systems X; 82141H (2012) https://doi.org/10.1117/12.908661
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Bacterial related infections are a burden on the healthcare industry. A system was built to test the efficacy of laser generated shockwaves on S. epidermidis biofilms (RP62A) grown on polystyrene surfaces. The system is based on a Qswitched, ND:YAG pulsed laser with an output wavelength of 1.064 μm that ablates titanium-coated soda-lime glass. Results show that the system is capable of generating stress profiles that can effectively delaminate biofilm structures from polymer surfaces.

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Artemio Navarro, Zachary D. Taylor, Anthony Z. Matolek, Ahuva Weltman, Vidyunmala Ramaprasad, Sean Huang, David O. Beenhouwer, David A. Haake, Vijay Gupta, and Warren S. Grundfest "Bacterial biofilm disruption using laser-generated shockwaves", Proc. SPIE 8214, Advanced Biomedical and Clinical Diagnostic Systems X, 82141H (28 February 2012); https://doi.org/10.1117/12.908661

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