Characterization and performance of commercial localized surface plasmon resonance chips

Daniele Gerion

doi:10.1117/12.917241

6 February 2012 Characterization and performance of commercial localized surface plasmon resonance chips

Daniele Gerion

Author Affiliations +

Proceedings Volume 8234, Plasmonics in Biology and Medicine IX; 823412 (2012) https://doi.org/10.1117/12.917241
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

We present a commercial platform for both label-free and labeled bioanalysis based on Localized Surface Plasmon Resonance. The platform relies on mass-produced nanostructured thin films with robust and reproducible plasmon resonances. The physical properties of these films (reproducibility, optical properties) as well as their stability, noise level, and intrinsic detection limits will be discussed. Also, we will illustrate the performance and strength of the platform in real-life assays. We will show how the sensitivity barrier can be lowered from the ng/mL range to the pg/mL range using the very same chip and different implementations. The examples will demonstrate how rich, fast, simple and reliable the platform is.

Citation Download Citation

Daniele Gerion "Characterization and performance of commercial localized surface plasmon resonance chips", Proc. SPIE 8234, Plasmonics in Biology and Medicine IX, 823412 (6 February 2012); https://doi.org/10.1117/12.917241

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