Design and simulation of label-free biosensor based on the dynamic distributed feedback laser emission

Fengyu Gao; Lujian Chen; Xiaozhong Wang; Sensen Li; Zhiping Cai

doi:10.1117/12.905544

29 November 2011 Design and simulation of label-free biosensor based on the dynamic distributed feedback laser emission

Fengyu Gao, Lujian Chen, Xiaozhong Wang, Sensen Li, Zhiping Cai

Proceedings Volume 8311, Optical Sensors and Biophotonics III; 83112J (2011) https://doi.org/10.1117/12.905544
Event: SPIE/OSA/IEEE Asia Communications and Photonics, 2011, Shanghai, China

Abstract

Label-free biosensor based on the dynamic distributed feedback (DFB) laser emission is proposed. The sensitivity of the sensor is substantially realized by the refractive index of the cladding layer that influences the effective refractive index (n_eff) of the whole waveguide structure. The designed multilayer structure consists of the substrate (n=1.51), the low refractive index mesoporous silica film (n=1.1~1.3), the dye-doped gain layer (n=1.58) and the high refractive index TiO₂ (n=2.1) thin film. We used the finite difference time domain (FDTD) algorithm to simulate the influence of the mesoporous silica film and the TiO₂ layer to the neff of the fundamental transverse electric (TE0) mode and the sensitivity in the DFB structure. It was found that the increase of refractive index of the mesoporous silica and the thickness of TiO₂ layer can slightly increase the n_eff of the structure. And the sensitivity of the sensor can be enhanced not only by the introduction of mesoporous silica, but also by a thicker TiO₂ layer.

Citation Download Citation

Fengyu Gao, Lujian Chen, Xiaozhong Wang, Sensen Li, and Zhiping Cai "Design and simulation of label-free biosensor based on the dynamic distributed feedback laser emission", Proc. SPIE 8311, Optical Sensors and Biophotonics III, 83112J (29 November 2011); https://doi.org/10.1117/12.905544

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