CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 8580 > Article
Paper
1 March 2013 On-off intermittency of thalamo-cortical neuronal network oscillations in the electroencephalogram of rodents with genetic predisposition to absence epilepsy
Alexander E. Hramov, Vadim V. Grubov, Alexey N. Pavlov, Evgenija Yu. Sitnikova, Alexey A. Koronovskii, Anastasija E. Runnova, Sveltlana A. Shurugina, Alexey V. Ivanov
Author Affiliations +
Proceedings Volume 8580, Dynamics and Fluctuations in Biomedical Photonics X; 85801E (2013) https://doi.org/10.1117/12.2001894
Event: SPIE BiOS, 2013, San Francisco, California, United States
Abstract
Spike-wave discharges are electroencephalographic hallmarks of absence epilepsy. Spike-wave discharges are known to originate from thalamo-cortical neuronal network that normally produces sleep spindle oscillations. Although both sleep spindles and spike-wave discharges are considered as thalamo-cortical oscillations, functional relationship between them is still uncertain. The present study describes temporal dynamics of spike-wave discharges and sleep spindles as determined in long-time electroencephalograms (EEG) recorded in WAG/Rij rat model of absence epilepsy. We have proposed the wavelet-based method for the automatic detection of spike-wave discharges, sleep spindles (10–15Hz) and 5–9Hz oscillations in EEG. It was found that non-linear dynamics of spike-wave discharges and sleep spindles fits well to the law of ’on-off intermittency’. Intermittency in sleep spindles and spike-wave discharges implies that (1) temporal dynamics of these oscillations are deterministic in nature, and (2) it might be controlled by a system-level mechanism responsible for circadian modulation of neuronal network activity.
© (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Alexander E. Hramov, Vadim V. Grubov, Alexey N. Pavlov, Evgenija Yu. Sitnikova, Alexey A. Koronovskii, Anastasija E. Runnova, Sveltlana A. Shurugina, and Alexey V. Ivanov "On-off intermittency of thalamo-cortical neuronal network oscillations in the electroencephalogram of rodents with genetic predisposition to absence epilepsy", Proc. SPIE 8580, Dynamics and Fluctuations in Biomedical Photonics X, 85801E (1 March 2013); https://doi.org/10.1117/12.2001894
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 7 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Electroencephalography
Spindles
Wavelets
Epilepsy
Continuous wavelet transforms
Nonlinear dynamics
Genetics
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top