Porcine pulmonary artery distension during static pressure inflation

Yik Ching Lee; Alys Clark; Mathew Fuld; Susan Haynes; Abhay Divekar; Eric Hoffman; Merryn Tawhai

doi:10.1117/12.2006695

29 March 2013 Porcine pulmonary artery distension during static pressure inflation

Yik Ching Lee, Alys Clark, Mathew Fuld, Susan Haynes, Abhay Divekar, Eric Hoffman, Merryn Tawhai

Proceedings Volume 8672, Medical Imaging 2013: Biomedical Applications in Molecular, Structural, and Functional Imaging; 867208 (2013) https://doi.org/10.1117/12.2006695
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

To improve the definition of the geometrical and mechanical properties of the porcine pulmonary arteries, we utilized an in vivo imaging-based approach to quantify the influence of static extravascular pressure change on pulmonary arterial geometry. The cross-sectional area and distance from the inlet of pulmonary arteries of two animals were measured over a range of static airway inflation pressure (7 cmH₂O - 25 cmH₂O, i.e. 0.69 kPa – 2.45 kPa). Vessels with diameter range of approximately 2.0 mm to 5.5 mm at airway inflation pressure of 25 cmH₂O (2.45kPa) were considered. The results suggest that lung inflation stretches the vessels laterally, but has no statistically significant effect on diameter.

Citation Download Citation

Yik Ching Lee, Alys Clark, Mathew Fuld, Susan Haynes, Abhay Divekar, Eric Hoffman, and Merryn Tawhai "Porcine pulmonary artery distension during static pressure inflation", Proc. SPIE 8672, Medical Imaging 2013: Biomedical Applications in Molecular, Structural, and Functional Imaging, 867208 (29 March 2013); https://doi.org/10.1117/12.2006695

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