Magnetic trapping of single molecules: principles, developments, and applications

W. Grange; T. R. Strick

doi:10.1117/12.2027050

12 September 2013 Magnetic trapping of single molecules: principles, developments, and applications

W. Grange, T. R. Strick

Proceedings Volume 8810, Optical Trapping and Optical Micromanipulation X; 88101H (2013) https://doi.org/10.1117/12.2027050
Event: SPIE NanoScience + Engineering, 2013, San Diego, California, United States

Abstract

Over the last decade, magnetic trapping has emerged as a tool which can complement the optical trap in certain key biophysical assays. Through its low cost, ease of use, stability and scalability, magnetic trapping is an attractive tool for micro-rheological analysis, generation of sorting structures for microfluidics, and also single-molecule experimentation. Here we will compare and contrast optical and magnetic trapping as they pertain to singlemolecule experimentation, and in particular to the study of interactions between single molecules such as proteins and nucleic acids.

Citation Download Citation

W. Grange and T. R. Strick "Magnetic trapping of single molecules: principles, developments, and applications", Proc. SPIE 8810, Optical Trapping and Optical Micromanipulation X, 88101H (12 September 2013); https://doi.org/10.1117/12.2027050

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