Photoacoustic tomography of unlabelled red blood cell at the nanoscale

Pratik Samant; Jian Chen; Liangzhong Xiang

doi:10.1117/12.2237530

15 September 2016 Photoacoustic tomography of unlabelled red blood cell at the nanoscale

Pratik Samant, Jian Chen, Liangzhong Xiang

Proceedings Volume 9925, Nanoimaging and Nanospectroscopy IV; 992506 (2016) https://doi.org/10.1117/12.2237530
Event: SPIE Nanoscience + Engineering, 2016, San Diego, California, United States

Abstract

In this letter, we present the principle behind nanoscale photoacoustic tomography (nPAT), in addition to simulation results demonstrating the thermal safety and the diagnostic potential of such a modality. Nanoscale photoacoustic tomography is a novel biomedical imaging modality that can allow for the 3D imaging of cells at nanometer resolutions. This modality also allows for the imaging of single red blood cells (RBCs) such that the hemoglobin concentration quantities can be visualized within the cell. As a result, we believe that nPAT can allow for diagnostic information at unprecedented resolutions and enable the visualization of previously unseen phenomenon in RBCs.

Conference Presentation

Citation Download Citation

Pratik Samant, Jian Chen, and Liangzhong Xiang "Photoacoustic tomography of unlabelled red blood cell at the nanoscale", Proc. SPIE 9925, Nanoimaging and Nanospectroscopy IV, 992506 (15 September 2016); https://doi.org/10.1117/12.2237530

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